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1
Investigating the effect of changing parameters when building prediction models in post-stroke aphasia
In: Nat Hum Behav (2020)
Abstract: Neuroimaging has radically improved our understanding of how speech and language abilities map to the brain in normal and impaired participants, including the diverse, graded variations observed in post-stroke aphasia. A handful of studies have begun to explore the reverse inference: creating brain-to-behaviour prediction models. In this study, we explored the effect of three critical parameters on model performance: (1) brain partitions as predictive features; (2) combination of multimodal neuroimaging; and (3) type of machine learning algorithms. We explored the influence of these factors while predicting four principal dimensions of language and cognition variation in post-stroke aphasia. Across all four behavioural dimensions, we consistently found that prediction models derived from diffusion weighted data did not improve performance over and above models using structural measures extracted from T1 scans. Our results provide a set of principles to guide future work aiming to predict outcomes in neurological patients from brain imaging data.
Keyword: Article
URL: https://doi.org/10.1038/s41562-020-0854-5
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7116235/
http://www.ncbi.nlm.nih.gov/pubmed/32313234
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2
Predicting the pattern and severity of chronic post-stroke language deficits from functionally-partitioned structural lesions
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3
Triangulation of language-cognitive impairments, naming errors and their neural bases post-stroke
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4
Seeing the Meaning: Top–Down Effects on Letter Identification
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5
Do You Read How I Read? Systematic Individual Differences in Semantic Reliance amongst Normal Readers
Woollams, Anna M.; Lambon Ralph, Matthew A.; Madrid, Gaston. - : Frontiers Media S.A., 2016
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6
Processing deficits for familiar and novel faces in patients with left posterior fusiform lesions
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7
Triangulation of the neurocomputational architecture underpinning reading aloud
Hoffman, Paul; Lambon Ralph, Matthew A.; Woollams, Anna M.. - : National Academy of Sciences, 2015
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8
What lies beneath: A comparison of reading aloud in pure alexia and semantic dementia
In: Cognitive neuropsychology. - Abingdon : Routledge, Taylor & Francis Group 31 (2014) 5, 461-481
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9
Capturing multidimensionality in stroke aphasia: mapping principal behavioural components to neural structures
Butler, Rebecca A.; Lambon Ralph, Matthew A.; Woollams, Anna M.. - : Oxford University Press, 2014
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10
Capturing multidimensionality in stroke aphasia: mapping principal behavioural components to neural structures
Butler, Rebecca A.; Lambon Ralph, Matthew A.; Woollams, Anna M.. - : Oxford University Press, 2014
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11
Repetition priming of picture naming in semantic aphasia: the impact of intervening items
In: Aphasiology. - London [u.a.] : Routledge, Taylor & Francis Group 26 (2012) 1, 44-63
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12
"W" is for bath: can associative errors be cued?
In: Journal of neurolinguistics. - Orlando, Fla. : Elsevier 24 (2011) 4, 445-465
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13
"L" is for tiger: effects of phonological (mis)cueing on picture naming in semantic aphasia
In: Journal of neurolinguistics. - Orlando, Fla. : Elsevier 22 (2009) 6, 538-547
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14
“L” is for tiger: Effects of phonological (mis)cueing on picture naming in semantic aphasia
In: Journal of neurolinguistics. - Orlando, Fla. : Elsevier 22 (2009) 6, 538-547
OLC Linguistik
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