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From genes to behavior in developmental dyslexia.
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In: ISSN: 1097-6256 ; EISSN: 1546-1726 ; Nature Neuroscience ; https://hal.archives-ouvertes.fr/hal-00260019 ; Nature Neuroscience, Nature Publishing Group, 2006, 9 (10), pp.1213-7. ⟨10.1038/nn1772⟩ (2006)
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Abstract:
International audience ; All four genes thus far linked to developmental dyslexia participate in brain development, and abnormalities in brain development are increasingly reported in dyslexia. Comparable abnormalities induced in young rodent brains cause auditory and cognitive deficits, underscoring the potential relevance of these brain changes to dyslexia. Our perspective on dyslexia is that some of the brain changes cause phonological processing abnormalities as well as auditory processing abnormalities; the latter, we speculate, resolve in a proportion of individuals during development, but contribute early on to the phonological disorder in dyslexia. Thus, we propose a tentative pathway between a genetic effect, developmental brain changes, and perceptual and cognitive deficits associated with dyslexia.
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Keyword:
[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology; [SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive Sciences; Animal; MESH: Animals; MESH: Behavior; MESH: Cognition Disorders; MESH: Disease Models; MESH: Dyslexia; MESH: Humans; MESH: Models; Molecular
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URL: https://doi.org/10.1038/nn1772
https://hal.archives-ouvertes.fr/hal-00260019
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| 2 |
Neurobiology of dyslexia: a reinterpretation of the data.
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In: ISSN: 0166-2236 ; EISSN: 1878-108X ; Trends in Neurosciences ; https://hal.archives-ouvertes.fr/hal-00242911 ; Trends in Neurosciences, Elsevier, 2004, 27 (12), pp.720-6. ⟨10.1016/j.tins.2004.10.004⟩ (2004)
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Should neuroconstructivism guide developmental research?
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In: ISSN: 1364-6613 ; Trends in Cognitive Sciences ; https://hal.archives-ouvertes.fr/hal-00260027 ; Trends in Cognitive Sciences, Elsevier, 2004, 8 (3), pp.100-1. ⟨10.1016/j.tics.2004.01.002⟩ (2004)
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Dyslexia. Talk of two theories.
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In: ISSN: 0028-0836 ; EISSN: 1476-4679 ; Nature ; https://hal.archives-ouvertes.fr/hal-00242898 ; Nature, Nature Publishing Group, 2001, 412 (6845), pp.393-5. ⟨10.1038/35086683⟩ (2001)
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