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Getting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomes
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Getting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomes
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Theis, Kevin R.; Dheilly, Nolwenn M.; Klassen, Jonathan L.; Brucker, Robert M.; Baines, John F.; Bosch, Thomas C. G.; Cryan, John F.; Gilbert, Scott F.; Goodnight, Charles J.; Lloyd, Elisabeth A.; Sapp, Jan; Vandenkoornhuyse, Philippe; Zilber-Rosenberg, Ilana; Rosenberg, Eugene; Bordenstein, Seth R.. - : American Society for Microbiology, 2016
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Abstract:
Given the complexity of host-microbiota symbioses, scientists and philosophers are asking questions at new biological levels of hierarchical organization—what is a holobiont and hologenome? When should this vocabulary be applied? Are these concepts a null hypothesis for host-microbe systems or limited to a certain spectrum of symbiotic interactions such as host-microbial coevolution? Critical discourse is necessary in this nascent area, but productive discourse requires that skeptics and proponents use the same lexicon.
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Keyword:
Perspective
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URL: http://www.ncbi.nlm.nih.gov/pubmed/27822520 https://doi.org/10.1128/mSystems.00028-16 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069740/
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