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Dynamic functional brain network connectivity during pseudoword processing relates to children’s reading skill
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| 2 |
Development of a standard of care for patients with valosin-containing protein associated multisystem proteinopathy.
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In: Orphanet journal of rare diseases, vol 17, iss 1 (2022)
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Family history of FXTAS is associated with age-related cognitive-linguistic decline among mothers with the FMR1 premutation.
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In: Journal of neurodevelopmental disorders, vol 14, iss 1 (2022)
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Cortical microstructure in primary progressive aphasia: a multicenter study.
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In: Alzheimer's research & therapy, vol 14, iss 1 (2022)
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Providing a parent-administered outcome measure in a bilingual family of a father and a mother of two adolescents with ASD: brief report.
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In: Developmental neurorehabilitation, vol 25, iss 2 (2022)
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Open access dataset of task-free hemodynamic activity in 4-month-old infants during sleep using fNIRS. ...
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Human cortical encoding of pitch in tonal and non-tonal languages.
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In: Nature communications, vol 12, iss 1 (2021)
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Resting functional connectivity in the semantic appraisal network predicts accuracy of emotion identification.
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| 9 |
Neural dynamics of semantic categorization in semantic variant of primary progressive aphasia.
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Borghesani, V; Dale, CL; Lukic, S; Hinkley, Lbn; Lauricella, M; Shwe, W; Mizuiri, D; Honma, S; Miller, Z; Miller, B; Houde, JF; Gorno-Tempini, ML; Nagarajan, SS. - : eScholarship, University of California, 2021
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Abstract:
Semantic representations are processed along a posterior-to-anterior gradient reflecting a shift from perceptual (e.g., it has eight legs) to conceptual (e.g., venomous spiders are rare) information. One critical region is the anterior temporal lobe (ATL): patients with semantic variant primary progressive aphasia (svPPA), a clinical syndrome associated with ATL neurodegeneration, manifest a deep loss of semantic knowledge. We test the hypothesis that svPPA patients perform semantic tasks by over-recruiting areas implicated in perceptual processing. We compared MEG recordings of svPPA patients and healthy controls during a categorization task. While behavioral performance did not differ, svPPA patients showed indications of greater activation over bilateral occipital cortices and superior temporal gyrus, and inconsistent engagement of frontal regions. These findings suggest a pervasive reorganization of brain networks in response to ATL neurodegeneration: the loss of this critical hub leads to a dysregulated (semantic) control system, and defective semantic representations are seemingly compensated via enhanced perceptual processing.
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Keyword:
2.1 Biological and endogenous factors; Aged; anterior temporal lobe; Aphasia; Basic Behavioral and Social Science; Behavioral and Social Science; Biochemistry and Cell Biology; Brain Disorders; Clinical Research; Female; human; Humans; magnetoencephalography; Male; Mental Health; Middle Aged; Nerve Degeneration; Neurons; neuroscience; Neurosciences; Primary Progressive; primary progressive aphasia; semantic categorization; semantic dementia; semantic variant ppa; Semantics; Temporal Lobe
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URL: https://escholarship.org/uc/item/6s23q3d9
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| 10 |
Resting functional connectivity in the semantic appraisal network predicts accuracy of emotion identification.
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| 11 |
A Therapeutic Relational Agent for Reducing Problematic Substance Use (Woebot): Development and Usability Study.
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In: Journal of medical Internet research, vol 23, iss 3 (2021)
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| 12 |
A Bayesian optimization approach for rapidly mapping residual network function in stroke. ...
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| 13 |
Age-related differences in the neural bases of phonological and semantic processes in the context of task-irrelevant information.
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| 14 |
Age-related differences in the neural bases of phonological and semantic processes.
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Age-related differences in resolving semantic and phonological competition during receptive language tasks.
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Sustained neural rhythms reveal endogenous oscillations supporting speech perception. ...
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Language networks in aphasia and health: A 1000 participant activation likelihood estimation meta-analysis. ...
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A Bayesian optimization approach for rapidly mapping residual network function in stroke.
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| 19 |
Expressive language development in adolescents with Down syndrome and fragile X syndrome: change over time and the role of family-related factors.
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In: Journal of neurodevelopmental disorders, vol 12, iss 1 (2020)
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New directions in clinical trials for frontotemporal lobar degeneration: Methods and outcome measures.
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In: Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 1 (2020)
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