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Functional Connectivity and Speech Entrainment Speech Entrainment Improves Connectivity Between Anterior and Posterior Cortical Speech Areas in Non-fluent Aphasia ...
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Functional Connectivity and Speech Entrainment Speech Entrainment Improves Connectivity Between Anterior and Posterior Cortical Speech Areas in Non-fluent Aphasia ...
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Speech Entrainment Improves Connectivity Between Anterior and Posterior Cortical Speech Areas in Non-Fluent Aphasia
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In: Neurorehabil Neural Repair (2022)
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Isolating the white matter circuitry of the dorsal language stream: Connectome‐Symptom Mapping in stroke induced aphasia
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In: Hum Brain Mapp (2021)
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Independent contributions of structural and functional connectivity: Evidence from a stroke model
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In: Netw Neurosci (2021)
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Abstract:
Altered functional connectivity is related to severity of language impairment in poststroke aphasia. However, it is not clear whether this finding specifically reflects loss of functional coherence, or more generally, is related to decreased structural connectivity due to cortical necrosis. The aim of the current study was to investigate this issue by factoring out structural connectivity from functional connectivity measures and then relating the residual data to language performance poststroke. Ninety-seven participants with a history of stroke were assessed using language impairment measures (Auditory Verbal Comprehension and Spontaneous Speech scores from the Western Aphasia Battery–Revised) and MRI (structural, diffusion tensor imaging, and resting-state functional connectivity). We analyzed the association between functional connectivity and language and controlled for multiple potential neuroanatomical confounders, namely structural connectivity. We identified functional connections within the left hemisphere ventral stream where decreased functional connectivity, independent of structural connectivity, was associated with speech comprehension impairment. These connections exist in frontotemporal and temporoparietal regions. Our results suggest poor speech comprehension in aphasia is at least partially caused by loss of cortical synchrony in a left hemisphere ventral stream network and is not only reflective of localized necrosis or structural connectivity.
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Research Article
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URL: https://doi.org/10.1162/netn_a_00207 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746188/
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2018 ASHA Research Symposium: Julius Fridricksson, BDNF Genotype & Brain Activation in Aphasia ...
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2018 ASHA Research Symposium: Julius Fridricksson, BDNF Genotype & Brain Activation in Aphasia ...
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Machine learning‐based multimodal prediction of language outcomes in chronic aphasia
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In: Hum Brain Mapp (2020)
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2018 ASHA Research Symposium: Julius Fridricksson, BDNF Genotype & Brain Activation in Aphasia ...
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BDNF genotype & brain activation in aphasia (Kristinsson et al., 2019) ...
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BDNF genotype & brain activation in aphasia (Kristinsson et al., 2019) ...
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Progression of Aphasia Severity in the Chronic Stages of Stroke
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Leukoaraiosis is associated with a decline in language abilities in chronic aphasia
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In: Neurorehabil Neural Repair (2019)
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Cortical and structural-connectivity damage correlated with impaired syntactic processing in aphasia
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Brain-Derived Neurotrophic Factor Genotype–Specific Differences in Cortical Activation in Chronic Aphasia
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